DRSN4MCPRED: ACCURATELY PREDICTING SITES OF DNA N4-METHYLCYTOSINE USING DEEP RESIDUAL SHRINKAGE NETWORK FOR DIAGNOSIS AND TREATMENT OF GASTROINTESTINAL CANCER IN THE PRECISION MEDICINE ERA

DRSN4mCPred: accurately predicting sites of DNA N4-methylcytosine using deep residual shrinkage network for diagnosis and treatment of gastrointestinal cancer in the precision medicine era

IntroductionThe DNA N4-methylcytosine (4mC) site levels of those suffering from digestive system cancers were higher, 02 Sensor and the pathogenesis of digestive system cancers may also be related to the changes in DNA 4mC levels.Identifying DNA 4mC sites is a very important step in studying the analysis of biological function and cancer prediction

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Short-term effects of a physical activity intervention on obesity and cardiovascular fitness of 12-14-year-old boy students

Background: Some local governments have implemented strategies to increase physical activity as a way 02 Sensor to control obesity in children, but in Iranian students few studies have evaluated the effects of such interventions on overweight and obese children.The aim of this study was to evaluate the effects of a short-term school-based physical

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Tissue-Resident Innate Immune Cell-Based Therapy: A Cornerstone of Immunotherapy Strategies for Cancer Treatment

Cancer immunotherapy has led to impressive advances in cancer treatment.Unfortunately, in a high percentage of patients is difficult to consistently restore immune responses to eradicate established tumors.It is well accepted that adaptive immune cells, such as B lymphocytes, CD4+ helper T lymphocytes, and CD8+ cytotoxic T-lymphocytes (CTLs), are t

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